1 Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, and Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Tennessee Valley Health System - Nashville Veterans Affairs Hospital Geriatric Research, Education, and Clinical Center (GRECC), Nashville, TN, USA. Electronic address: wes.ely@vumc.org.