Engaging the spikes: heparan sulfate facilitates SARS-CoV-2 spike protein binding to ACE2 and potentiates viral infection

Signal Transduct Target Ther. 2021 Jan 29;6(1):39. doi: 10.1038/s41392-021-00470-1.

Rajkumar Singh Kalra^{1

2}, Ramesh Kandimalla^{3

4}

¹ AIST-INDIA DAILAB, National Institute of Advanced Industrial Science & Technology (AIST), Higashi 1-1-1, Tsukuba, Japan. rajkumar-singh@oist.jp.
² Immune Signal Unit, Okinawa Institute of Science and Technology Graduate University, 1919-1 Tancha, Onna-son, Okinawa, 904-0495, Japan. rajkumar-singh@oist.jp.
³ Applied Biology, CSIR-Indian Institute of Chemical Technology (IICT), Uppal Road, Tarnaka, Hyderabad, Telangana State, India. ramesh.kandimalla@iict.res.in.
⁴ Department of Biochemistry, Kakatiya Medical College, Warangal, Telangana, 506004, India. ramesh.kandimalla@iict.res.in.

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