Increased Incidence of IKZF1 deletions and IGH-CRLF2 translocations in B-ALL of Hispanic/Latino children-a novel health disparity

Leukemia. 2021 Aug;35(8):2399-2402. doi: 10.1038/s41375-021-01133-4. Epub 2021 Feb 2.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biomarkers, Tumor / genetics
  • Child
  • Female
  • Follow-Up Studies
  • Gene Deletion*
  • Health Status Disparities*
  • Hispanic or Latino / genetics*
  • Humans
  • Ikaros Transcription Factor / genetics*
  • Immunoglobulin Heavy Chains / genetics*
  • Incidence
  • Male
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / epidemiology
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / genetics
  • Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / pathology*
  • Prognosis
  • Receptors, Cytokine / genetics*
  • Translocation, Genetic*
  • United States / epidemiology

Substances

  • Biomarkers, Tumor
  • CRLF2 protein, human
  • IKZF1 protein, human
  • Immunoglobulin Heavy Chains
  • Receptors, Cytokine
  • Ikaros Transcription Factor