Pain and functional outcomes of the sacroiliac joint after platelet-rich plasma injection: a descriptive review

Regen Med. 2021 Jan;16(1):87-100. doi: 10.2217/rme-2020-0110. Epub 2021 Feb 3.

Abstract

The purpose of this manuscript is to highlight and review the status of literature regarding efficacy of platelet-rich plasma (PRP) in the treatment of sacroiliac joint (SIJ) dysfunction. A review of the literature on PRP interventions on the SIJ or ligaments was performed. Seven studies had improvements in their respective primary end point and demonstrated a strong safety profile without any serious adverse events. Only five articles demonstrated clinical efficacy of >50% in their primary outcome measures. There appears to be inconsistent and insufficient evidence for a conclusive recommendation for or against SIJ PRP. There is a need for adequately powered well-designed, standardized, double-blinded randomized clinical trials to determine the effectiveness of PRP in SIJ-mediated pain.

Keywords: bone and cartilage; chronic pain; hip pain; low back pain; musculoskeletal and joint disorders; orthopaedics; platelet-rich plasma; regenerative medicine; sacroiliac joint; sports medicine.

Publication types

  • Review

MeSH terms

  • Back Pain
  • Humans
  • Low Back Pain*
  • Platelet-Rich Plasma*
  • Sacroiliac Joint
  • Treatment Outcome