A Rare Case of a Pediatric Patient Affected by Crossed Fused Renal Ectopia: The usefulness of Dual Tracer99mTc-Diethylenetriamine Pentaacetic Acid/99mTc-Dimercaptosuccinic Acid Scintigraphy

Luca Filippi; Oreste Bagni; Alessia Marcellino; Riccardo Lubrano

doi:10.4103/ijnm.IJNM_136_20

A Rare Case of a Pediatric Patient Affected by Crossed Fused Renal Ectopia: The usefulness of Dual Tracer^99mTc-Diethylenetriamine Pentaacetic Acid/^99mTc-Dimercaptosuccinic Acid Scintigraphy

Indian J Nucl Med. 2020 Oct-Dec;35(4):374-376. doi: 10.4103/ijnm.IJNM_136_20. Epub 2020 Oct 21.

Authors

Luca Filippi¹, Oreste Bagni¹, Alessia Marcellino², Riccardo Lubrano²

Affiliations

¹ Department of Nuclear Medicine, Santa Maria Goretti Hospital, Latina, Italy.
² Department of Maternal and Child Health, UOC of Latina, University of La Sapienza Roma, Roma, Italy.

Abstract

A 9-year-old male patient, with an ultrasonography diagnosis of horseshoe kidney condition, was referred to our hospital for recurrent urinary tract infection. He was submitted to ^99mTc-diethylenetriamine pentaacetic acid sequential scintigraphy that demonstrated urine stasis in the calyces of both kidneys and was also suggestive for 8-shaped right-to-left crossed-fused renal ectopia. A subsequently performed ^99mTc-dimercaptosuccinic acid scan confirmed the diagnosis of crossed renal ectopia, also disclosing, through single-photon emission computed tomography (SPECT) acquisition, cortical uptake defects in both kidneys, and indicative of renal scarring due to recurrent pyelonephritis. Combined scintigraphy and appropriate technological approaches (SPECT/3D volume rendering) may be useful in selected patients with congenital anomalies.

Keywords: 99mTc-diethylenetriamine pentaacetic acid; 99mTc-dimercaptosuccinic acid; congenital abnormalities; renal scintigraphy; single-photon emission computed tomography.