Non-regioselective functionalization: an underestimate chemical diversity generator in medicinal chemistry

Sara Guariento; Matteo Biagetti; Paolo Ronchi

doi:10.4155/fmc-2021-0011

Non-regioselective functionalization: an underestimate chemical diversity generator in medicinal chemistry

Future Med Chem. 2021 Apr;13(7):595-599. doi: 10.4155/fmc-2021-0011. Epub 2021 Mar 4.

Authors

Sara Guariento¹, Matteo Biagetti¹, Paolo Ronchi¹

Affiliation

¹ Chemistry Research & Drug Design, Chiesi Farmaceutici S.p.A, Centro Ricerche, Largo Belloli 11/a, Parma 43122, Italy.

PMID: 33657835
DOI: 10.4155/fmc-2021-0011

No abstract available

Keywords: C-H activation; DOS; LSF; chemical diversity; diversity-oriented synthesis; late-stage functionalization; medicinal chemistry innovation; non-regioselective functionalization; regioselectivity.

Publication types

Editorial

MeSH terms

Chemistry, Pharmaceutical
Molecular Structure
Pharmaceutical Preparations / chemical synthesis
Pharmaceutical Preparations / chemistry*
Stereoisomerism

Substances

Pharmaceutical Preparations