Body composition assessment after pediatric liver transplant

JPEN J Parenter Enteral Nutr. 2022 Jan;46(1):172-179. doi: 10.1002/jpen.2105. Epub 2021 Apr 26.

Abstract

Background: Pediatric liver transplantation generally restores metabolic function; yet after transplantation, some children remain malnourished, have increased adiposity, and develop obesity. Measurement of body composition in the assessment of nutrition status could reduce adverse consequences in children.

Methods: Anthropometric measurements, multiple-frequency bioelectrical impedance analysis, air displacement plethysmography, and ultrasound measurements were conducted on children recruited from the liver transplant program at the University of Minnesota Masonic Children's Hospital. A cross-sectional study was conducted to describe the quality of weight gain in post-liver transplant children between the ages of 2 and 17 years using multiple assessment tools (air displacement plethysmography, multiple-frequency bioelectrical impedance analysis, and ultrasound) and to determine whether multiple-frequency bioelectrical impedance analysis and ultrasound accurately describe body composition and quality of weight gain.

Results: Mean percent body fat by air displacement plethysmography and multiple-frequency bioelectrical impedance analysis was 18.4% (±3.3) and 19.0% (±3.9), respectively (P > .99). There were insufficient data to examine the relationship between summed muscle and adipose thickness measures by ultrasound and percent body fat determined by air displacement plethysmography or multiple-frequency bioelectrical impedance analysis.

Conclusion: Percent body fat, fat mass, and fat-free mass measures determined by air displacement plethysmography and multiple-frequency bioelectrical impedance analysis were not statistically different, which suggests the stand-on device used in this study could be a useful body composition assessment tool for the pediatric population.

Keywords: body composition; liver transplant; nutrition assessment; pediatrics.

MeSH terms

  • Adipose Tissue
  • Adolescent
  • Body Composition / physiology
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Electric Impedance
  • Humans
  • Liver Transplantation*
  • Plethysmography