Eosinophils interact with thymocytes and proliferate in the human thymus

Sofie Albinsson; Christine Lingblom; Christina Lundqvist; Esbjörn Telemo; Olov Ekwall; Christine Wennerås

doi:10.1002/eji.202049080

Eosinophils interact with thymocytes and proliferate in the human thymus

Eur J Immunol. 2021 Jun;51(6):1539-1541. doi: 10.1002/eji.202049080. Epub 2021 Mar 11.

Authors

Sofie Albinsson¹, Christine Lingblom^{1

2}, Christina Lundqvist³, Esbjörn Telemo³, Olov Ekwall^{3

4}, Christine Wennerås^{1

2}

Affiliations

¹ Department of Infectious Diseases, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
² Department of Clinical Microbiology, Sahlgrenska University Hospital, Gothenburg, Region Västra Götaland, Sweden.
³ Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
⁴ Department of Pediatrics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

PMID: 33686667
DOI: 10.1002/eji.202049080

Abstract

Eosinophils differentiate and mature in the thymus, outside of the bone marrow, in healthy individuals. Locally developed thymic eosinophils may contribute to the maturation and selection of human thymocytes.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Antigens, CD34 / metabolism
Cell Communication
Cell Proliferation
Cells, Cultured
Clonal Selection, Antigen-Mediated
Eosinophils / immunology*
Galectins / metabolism
Humans
Thymocytes / immunology*
Thymus Gland / immunology*

Substances

Antigens, CD34
Galectins
galectin 10, human