Case Report: Early Transplant Rejection of a Methanol-Intoxicated Donor Heart in a Young Female Patient. A Diagnostic Approach With CMR, Cardiac Biopsy, and Genetic Risk Assessment

Front Immunol. 2021 Feb 22:11:575635. doi: 10.3389/fimmu.2020.575635. eCollection 2020.

Abstract

This case report describes the contributions of multimodality imaging, cardiac biopsy, and genetic sequencing to the diagnosis and management of heart transplant rejection in a 23-year old patient with dilated cardiomyopathy.

Keywords: cardiac magnetic resonance imaging (CMR); cardiomyopathy; gene sequence; heart transplantation; mapping - magnetic resonance imaging.

Publication types

  • Case Reports

MeSH terms

  • Alcoholic Intoxication / complications*
  • Alcoholic Intoxication / diagnosis
  • Biopsy
  • Cardiomyopathy, Dilated / diagnosis
  • Cardiomyopathy, Dilated / physiopathology
  • Cardiomyopathy, Dilated / surgery*
  • Diagnosis, Differential
  • Donor Selection
  • Female
  • Genetic Predisposition to Disease
  • Graft Rejection / diagnosis*
  • Graft Rejection / etiology
  • Graft Rejection / genetics
  • Graft Rejection / therapy
  • Heart Failure / diagnosis
  • Heart Failure / physiopathology
  • Heart Failure / surgery*
  • Heart Transplantation / adverse effects*
  • Humans
  • Magnetic Resonance Imaging*
  • Methanol / poisoning*
  • Middle Aged
  • Molecular Diagnostic Techniques*
  • Predictive Value of Tests
  • Risk Assessment
  • Risk Factors
  • Time Factors
  • Tissue Donors*
  • Treatment Outcome
  • Young Adult

Substances

  • Methanol