The main etiologic agent of tuberculosis (TB) in livestock is Mycobacterium bovis; human TB cases caused by M. bovis are rare. Analysis of a TB outbreak caused by polyresistant M. bovis involving a human and sympatric sheep in Spain suggests local circulation of drug-resistant M. bovis strains among livestock.
Keywords: Mycobacterium bovis; One Health; Spain; Tuberculosis; antimicrobial resistance; bacteria; drug resistance; livestock; sheep; tuberculosis and other mycobacteria; zoonoses.