ROS mediated apoptotic pathways in primary effusion lymphoma: Comment on induction of apoptosis by Shikonin through ROS-mediated intrinsic and extrinsic pathways in primary effusion lymphoma

Transl Oncol. 2021 Jul;14(7):101061. doi: 10.1016/j.tranon.2021.101061. Epub 2021 Apr 12.

Author

Pankaj Dwivedi¹

Affiliation

¹ Department of Microchemistry, Proteomics, and Lipidomics, Genentech Inc. 1 DNA Way, South San Francisco, CA 94080, United States. Electronic address: dwivedip@gene.com.

Abstract

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Mechanism of action of Shikonin against PEL.
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Therapeutic potential of Shikonin as an alternative herbal medicine.
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Interconnectivity among cellular stress, apoptosis pathways (extrinsic and intrinsic) and Shikonin.

Keywords: Apoptosis; Primary effusion lymphoma (PEL); ROS; Shikonin.