Novel Method of Calculating Pulse Pressure Variation to Predict Fluid Responsiveness to Transfusion in Very Low Birth Weight Infants

J Pediatr. 2021 Jul:234:265-268.e1. doi: 10.1016/j.jpeds.2021.04.012. Epub 2021 Apr 15.

Abstract

A novel technique was used to calculate pulse pressure variation. The algorithm reliably predicted fluid responsiveness to transfusion, with a receiver operating characteristic area under the curve of 0.89. This technique may assist clinicians in the management of fluids and vasoactive medications for premature infants.

MeSH terms

  • Algorithms*
  • Area Under Curve
  • Blood Pressure Determination / methods*
  • Erythrocyte Transfusion*
  • Female
  • Humans
  • Hypovolemia / physiopathology
  • Hypovolemia / therapy*
  • Infant, Newborn
  • Infant, Premature
  • Infant, Premature, Diseases / physiopathology
  • Infant, Premature, Diseases / therapy*
  • Infant, Very Low Birth Weight*
  • Male
  • ROC Curve
  • Retrospective Studies
  • Treatment Outcome