Short report: craniosynostosis, a late complication of nutritional rickets

J Pediatr Endocrinol Metab. 2021 Apr 16;34(8):1055-1060. doi: 10.1515/jpem-2020-0580. Print 2021 Aug 26.

Abstract

Objectives: Nutritional rickets may be a preventable cause of craniosynostosis. This potential association is under-recognised. A late diagnosis of craniosynostosis may result in reduced brain growth, raised intracranial pressure and long-term psychosocial problems.

Case presentation: We present four cases of craniosynostosis associated with nutritional rickets. Those who had delayed presentation underwent emergency craniotomy.

Conclusions: Treatment of nutritional rickets and early identification of craniosynostosis can reduce morbidity in these children.

Keywords: craniosynostosis; metabolic bone diseases; paediatrics; rickets complications; vitamin D deficiency.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Craniosynostoses / etiology
  • Craniosynostoses / pathology*
  • Familial Hypophosphatemic Rickets / complications*
  • Female
  • Humans
  • Infant
  • Male
  • Prognosis