Combined Technique for the Application of Micropulse Cyclophotocoagulation in Patients with Uncontrolled Glaucoma: Cyclo Mix

Loayza-Gamboa Waldo; Herrera-Quiroz Julio; Chávez-Vallejos Jennifer; Valderrama-Albino Vanessa; Córdova-Crisanto Luis; Alvarado-Villacorta Rosa; Valera-Cornejo Diego Alejandro

doi:10.5005/jp-journals-10078-1289

Combined Technique for the Application of Micropulse Cyclophotocoagulation in Patients with Uncontrolled Glaucoma: Cyclo Mix

J Curr Glaucoma Pract. 2020 Sep-Dec;14(3):93-97. doi: 10.5005/jp-journals-10078-1289.

Authors

Loayza-Gamboa Waldo¹, Herrera-Quiroz Julio², Chávez-Vallejos Jennifer¹, Valderrama-Albino Vanessa², Córdova-Crisanto Luis³, Alvarado-Villacorta Rosa², Valera-Cornejo Diego Alejandro²

Affiliations

¹ Glaucoma Department, Peruvian National Eye Institute "Francisco Contreras Campos", Lima, Perú; Research Department, Clínica Vista, Lima, Peru; Cayetano Heredia Peruvian University, Lima, Peru.
² Research Department, Clínica Vista, Lima, Peru; Cayetano Heredia Peruvian University, Lima, Peru.
³ Research Department, Clinica Vista, Lima, Peru; National University of San Marcos, Lima, Peru.

Abstract

Purpose: To describe the outcomes of a combined technique (Cyclo Mix) in uncontrolled glaucoma cases.

Materials and methods: Retrospective study. The Supra 810 nm subliminal laser (Quantel Medical, Cournon d'Auvergne, France) was used. A combined technique was performed using the subliminal mode (Subcyclo) in one hemifield (power of 2,000 mW, a duty cycle of 35%, and 80-150 seconds), and the continuous wave mode (Thermo Cyclo) on the other hemifield (power of 1,000 mW, exposure time of 2 seconds per spot). The primary endpoint was the probability of surgical failure. Mean intraocular pressure (IOP) change, best-corrected visual acuity (BCVA), number of glaucoma eye drops, and complications at 6 months postoperatively were secondary outcomes.

Results: Twenty-three eyes from 13 patients were included. Mean age was 61.4 ± 16.7 (range: 18-78 years), and 69% were female, with a baseline IOP of 20.3 ± 5.9 (range: 13-38 mm Hg). The cumulative probability of failure was 18 and 22% on days 90 and 180, respectively. Mean IOP reduction was -25.6 ± 20.9% at 6 months. The number of glaucoma eye drops was reduced to 1.2 ± 1 (p = 0.0024) at 6 months. No statistically significant change in the mean BCVA compared with baseline at 6 months was found (p = 0.84), and no severe complications were reported.

Conclusion: Cyclo Mix seems to be a safe therapy that effectively reduces the IOP and glaucoma medications in eyes with uncontrolled open-angle glaucoma for up to 6 months.

How to cite this article: Waldo L-G, Julio H-Q, Jennifer C-V, et al . Combined Technique for the Application of Micropulse Cyclophotocoagulation in Patients with Uncontrolled Glaucoma: Cyclo Mix. J Curr Glaucoma Pract 2020;14(3):93-97.

Keywords: Cyclodestruction; Glaucoma; Intraocular pressure; Micropulse laser; Transscleral cyclophotocoagulation.