Assessment of morbidity and mortality in newborns with late prematurity: experience of a reference maternity in the northeast of Brazil

Minerva Obstet Gynecol. 2022 Jun;74(3):270-278. doi: 10.23736/S2724-606X.21.04734-5. Epub 2021 Apr 20.

Abstract

Background: Late preterm infants show high rates of adverse perinatal outcomes. The aim of this study is to assess the morbidity and mortality of newborns (NBs) with late preterm birth in a reference maternity hospital in northeastern Brazil.

Methods: Retrospective cohort study from March 1st to July 15th, 2017. A total of 204 NBs with gestational age between 34 and 36 weeks and six days were evaluated and compared to 205 full-term NBs (39 and 40 weeks and six days). Perinatal outcomes including neonatal morbidity were evaluated. The Student's t and ANOVA tests were used for normal variables, and the Wilcoxon, Mann-Whitney and Kruskal-Wallis tests for non-normal variables.

Results: Late preterm infants showed significant higher rates of hypothermia, hypoglycemia, respiratory distress syndrome, jaundice in need of phototherapy (67.6%), admission to the neonatal intensive care unit (ICU), and difficulty breastfeeding compared to full-term NBs (P<0.001). Respiratory distress was the main indication for the admission of late preterm infants (P<0.001) to neonatal ICU. Late preterm infants had a longer hospital stay (6.9 vs. 3.7 days, P<0.001). There were three deaths in the group of late preterm NBs, and none in the group of term NBs.

Conclusions: Late preterm NBs presented higher rates of morbidity and mortality when compared to full-term NBs.

MeSH terms

  • Brazil / epidemiology
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Infant, Newborn, Diseases*
  • Infant, Premature
  • Infant, Premature, Diseases* / epidemiology
  • Morbidity
  • Pregnancy
  • Premature Birth* / epidemiology
  • Retrospective Studies