Genetic polymorphisms, vitamin D binding protein and vitamin D deficiency in COVID-19

Aduragbemi A Faniyi; Sebastian T Lugg; Sian E Faustini; Craig Webster; Joanne E Duffy; Martin Hewison; Adrian Shields; Peter Nightingale; Alex G Richter; David R Thickett

doi:10.1183/13993003.00653-2021

Genetic polymorphisms, vitamin D binding protein and vitamin D deficiency in COVID-19

Eur Respir J. 2021 May 6;57(5):2100653. doi: 10.1183/13993003.00653-2021. Print 2021 May.

Authors

Aduragbemi A Faniyi^{1

2}, Sebastian T Lugg^{1

2}, Sian E Faustini³, Craig Webster⁴, Joanne E Duffy⁴, Martin Hewison⁵, Adrian Shields^{3

4}, Peter Nightingale⁴, Alex G Richter^{3

4

6}, David R Thickett^{1

4

6}

Affiliations

¹ Birmingham Acute Care Research Group, Institute of Inflammation and Ageing, University of Birmingham, Birmingham, UK.
² Joint first authors.
³ Clinical Immunology Service, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.
⁴ University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
⁵ Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK.
⁶ Joint last authors.

Abstract

This work outlines the potential importance of vitamin D binding protein and vitamin D in immune function and COVID-19 infection https://bit.ly/3byTaO5

Publication types

Letter
Comment

MeSH terms

COVID-19*
Health Personnel
Humans
Polymorphism, Genetic
SARS-CoV-2
Seroconversion
United Kingdom
Vitamin D
Vitamin D Deficiency* / complications
Vitamin D Deficiency* / genetics
Vitamin D-Binding Protein / genetics

Substances

Vitamin D-Binding Protein
Vitamin D

Grants and funding

MR/S002782/1/MRC_/Medical Research Council/United Kingdom