Maternal Vitamin D Level and Attention-Deficit/Hyperactivity Disorder in Offspring: Getting the Most Out of the Data

Abstract

We read with great interest the article Sucksdorff et al. "Maternal Vitamin D Levels and the Risk of Offspring Attention-Deficit/Hyperactivity Disorder."¹ We commend the authors for this extraordinary work. Several studies have explored this association lately as well.² It is logistically challenging to conduct this type of study, as it requires long-term follow-up and patient compliance in a vulnerable population. In this letter, we aim to provide a few suggestions for the statistical methodological aspect, which can better guide the clinician in predicting ADHD among offspring.