Hair of the mouse: A skin bacteria "cocktail" gets follicles back on their feet

Jeanmarie R Gonzalez; Geil R Merana; Tiffany C Scharschmidt

doi:10.1016/j.chom.2021.04.011

Hair of the mouse: A skin bacteria "cocktail" gets follicles back on their feet

Cell Host Microbe. 2021 May 12;29(5):742-744. doi: 10.1016/j.chom.2021.04.011.

Authors

Jeanmarie R Gonzalez¹, Geil R Merana¹, Tiffany C Scharschmidt²

Affiliations

¹ Biomedical Sciences Program, University of California, San Francisco, CA 94143, USA; Department of Dermatology, University of California, San Francisco, CA 94143, USA.
² Department of Dermatology, University of California, San Francisco, CA 94143, USA. Electronic address: tiffany.scharschmidt@ucsf.edu.

PMID: 33984276
DOI: 10.1016/j.chom.2021.04.011

Abstract

Microbes can boost cutaneous immune defense and skin reparative capacity. However, mechanistic understanding, especially of the latter, remains sparse. In this issue of Cell Host & Microbe, Wang et al. (2021) shed light on this, demonstrating that bacteria contribute to hair follicle neogenesis after skin wounding via keratinocyte-intrinsic IL-1R1 signaling.

Publication types

Comment

MeSH terms

Animals
Bacteria
Hair Follicle*
Mice
Regeneration
Signal Transduction
Skin*

Abstract

Publication types

MeSH terms

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