Yolk Sac Tumour of the Ovary in Pregnancy Treated With Surgery and Chemotherapy: A Case Report

Alida J Pokoradi; Anita Agrawal

doi:10.1016/j.jogc.2021.04.013

Yolk Sac Tumour of the Ovary in Pregnancy Treated With Surgery and Chemotherapy: A Case Report

J Obstet Gynaecol Can. 2021 Oct;43(10):1177-1179. doi: 10.1016/j.jogc.2021.04.013. Epub 2021 May 14.

Authors

Alida J Pokoradi¹, Anita Agrawal²

Affiliations

¹ Department of Obstetrics and Gynaecology, Queen's University, Kingston, ON. Electronic address: apokoradi@qmed.ca.
² Department of Obstetrics and Gynaecology, Division of Gynaecologic Oncology, Queen's University, Kingston, ON.

PMID: 34000443
DOI: 10.1016/j.jogc.2021.04.013

Abstract

Background: Ovarian carcinoma diagnosed in pregnancy is rare. Treatment should take both mother and fetus into consideration.

Case: We present the case of a patient diagnosed with a stage IC1 yolk sac tumour of the ovary at 15 weeks gestation, who underwent surgical staging and adjuvant chemotherapy during pregnancy. Intrauterine growth restriction was diagnosed and the patient delivered by cesarean at 36 weeks gestation for obstructed labour.

Conclusion: Yolk sac tumour of the ovary in pregnancy with concomitant chemotherapy is uncommon. Adverse outcomes, including restricted fetal growth, are possible and their identification may help guide timing of delivery.

Keywords: chemotherapy; endodermal sinus tumor; intrauterine growth restriction; ovarian cancer; pregnancy.

Publication types

Case Reports

MeSH terms

Chemotherapy, Adjuvant
Endodermal Sinus Tumor* / diagnostic imaging
Endodermal Sinus Tumor* / drug therapy
Endodermal Sinus Tumor* / surgery
Female
Humans
Ovarian Neoplasms* / drug therapy
Ovarian Neoplasms* / surgery
Pregnancy
Yolk Sac