Eutos long-term survival score discriminates different Sokal score categories in chronic myeloid leukemia patients, showing better survival prediction. Analysis of the GIMEMA CML observational study

Massimo Breccia; Patrizia Pregno; Fausto Castagnetti; Massimiliano Bonifacio; Mario Tiribelli; Antonella Gozzini; Anna Rita Scortechini; Luigiana Luciano; Bruno Martino; Fabio Stagno; Giovanni Caocci; Gaetano La Barba; Michele Pizzuti; Giovannino Ciccone; Giuseppe Saglio; Giorgina Specchia

doi:10.1038/s41375-021-01292-4

Eutos long-term survival score discriminates different Sokal score categories in chronic myeloid leukemia patients, showing better survival prediction. Analysis of the GIMEMA CML observational study

Leukemia. 2021 Jun;35(6):1814-1816. doi: 10.1038/s41375-021-01292-4. Epub 2021 May 17.

Authors

Massimo Breccia¹, Patrizia Pregno², Fausto Castagnetti³, Massimiliano Bonifacio⁴, Mario Tiribelli⁵, Antonella Gozzini⁶, Anna Rita Scortechini⁷, Luigiana Luciano⁸, Bruno Martino⁹, Fabio Stagno¹⁰, Giovanni Caocci¹¹, Gaetano La Barba¹², Michele Pizzuti¹³, Giovannino Ciccone¹⁴, Giuseppe Saglio¹⁵, Giorgina Specchia¹⁶

Affiliations

¹ Department of Translational and Precision Medicine, Az. Policlinico Umberto I-Sapienza University, Rome, Italy. breccia@bce.uniroma1.it.
² Hematology Unit, Az Ospedaliero Universitaria Città' della Salute e della Scienza, Torino, Italy.
³ Institute of Hematology "L. and A. Seràgnoli", Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, "S. Orsola-Malpighi" Hospital, Bologna, Italy.
⁴ Department of Medicine, Section of Hematology, University of Verona, Verona, Italy.
⁵ Division of Hematology and BMT, Department of Medical Area, University of Udine, Udine, Italy.
⁶ Hematology Unit, AOU Careggi, University of Florence, Florence, Italy.
⁷ Division of Hematology, Azienda Ospedaliero Universitaria Ospedali Riuniti Ancona, Ancona, Italy.
⁸ Hematology Unit, Federico II University of Naples, Napoli, Italy.
⁹ Hematology Unit, A.O. Bianchi-Melacrino-Morelli, Reggio Calabria, Italy.
¹⁰ Hematology Section, Ferrarotto Hospital, Catania, Italy.
¹¹ Department of Medical Sciences and Public Health, University of Cagliari, Businco Hospital, Cagliari, Italy.
¹² Department of Hematology, "Spirito Santo" Hospital, Pescara, Italy.
¹³ Ematologia, Azienda Ospedaliera S. Carlo, Potenza, Italy.
¹⁴ Unit of Clinical Epidemiology, CPO Piemonte, AOU Città della Salute e della Scienza di Torino, Torino, Italy.
¹⁵ Divisione Universitaria di Ematologia e Terapie Cellulari, A.O. Ordine Mauriziano, Turin, Italy.
¹⁶ Hematology Section, Department of Emergency and Transplantation - GIMEMA WP CML, University of Bari Aldo Moro, Bari, Italy.

PMID: 34002030
DOI: 10.1038/s41375-021-01292-4

No abstract available

Publication types

Comparative Study
Letter
Observational Study

MeSH terms

Aged
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
Dasatinib / administration & dosage
Female
Follow-Up Studies
Humans
Imatinib Mesylate / administration & dosage
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / drug therapy
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / mortality*
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / pathology
Male
Middle Aged
Outcome Assessment, Health Care / methods*
Prognosis
Prospective Studies
Pyrimidines / administration & dosage
Retrospective Studies
Severity of Illness Index*
Survival Rate

Substances

Pyrimidines
Imatinib Mesylate
nilotinib
Dasatinib