Neutralizing Autoantibodies to Type I Interferons in COVID-19 Convalescent Donor Plasma

Sara E Vazquez; Paul Bastard; Kathleen Kelly; Adrian Gervais; Philip J Norris; Larry J Dumont; Jean-Laurent Casanova; Mark S Anderson; Joseph L DeRisi

doi:10.1007/s10875-021-01060-0

Neutralizing Autoantibodies to Type I Interferons in COVID-19 Convalescent Donor Plasma

J Clin Immunol. 2021 Aug;41(6):1169-1171. doi: 10.1007/s10875-021-01060-0. Epub 2021 May 19.

Authors

Sara E Vazquez¹, Paul Bastard^{2

3

4}, Kathleen Kelly⁵, Adrian Gervais^{2

3}, Philip J Norris^{6

5}, Larry J Dumont^{5

7

8}, Jean-Laurent Casanova^{2

3

4

9}, Mark S Anderson⁶, Joseph L DeRisi^{6

10}

Affiliations

¹ University of California, San Francisco, CA, USA. sara.vazquez@ucsf.edu.
² Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France.
³ University of Paris, Imagine Institute, Paris, France.
⁴ St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.
⁵ Vitalant Research Institute, Denver, CO, USA.
⁶ University of California, San Francisco, CA, USA.
⁷ University of Colorado School of Medicine, Aurora, CO, USA.
⁸ Geisel School of Medicine at Dartmouth, Lebanon, NH, USA.
⁹ Howard Hughes Medical Institute, New York, NY, USA.
¹⁰ Chan Zuckerberg Biohub, San Francisco, CA, USA.

No abstract available

Publication types

Letter
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Antibodies, Neutralizing / blood*
Autoantibodies / blood*
COVID-19 / immunology*
COVID-19 / therapy
COVID-19 Serotherapy
Convalescence
Humans
Immunization, Passive
Interferon Type I / immunology*
Male
Middle Aged
SARS-CoV-2 / physiology*
Tissue Donors

Substances

Antibodies, Neutralizing
Autoantibodies
Interferon Type I

Publication types

MeSH terms

Substances

Grants and funding