1 Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7‑3‑1 Hongo, Bunkyo‑ku, Tokyo, 113‑8655, Japan.
2 Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7‑3‑1 Hongo, Bunkyo‑ku, Tokyo, 113‑8655, Japan. mutsuoh@gmail.com.
3 Department of Advanced Clinical Science and Therapeutics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. mutsuoh@gmail.com.
4 Department of Advanced Translational Research and Medicine in Management of Pulmonary Hypertension, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
5 The School of Cardiovascular Medicine and Sciences, King's College London British Heart Foundation Centre of Excellence, London, UK.
6 Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7‑3‑1 Hongo, Bunkyo‑ku, Tokyo, 113‑8655, Japan. komuro-tky@umin.ac.jp.