Risk of muscle toxicity events for daptomycin with and without statins: Analysis of the Japanese Adverse Event Report database

Basic Clin Pharmacol Toxicol. 2021 Sep;129(3):268-272. doi: 10.1111/bcpt.13618. Epub 2021 Jun 23.

Authors

Tomoyuki Yamada¹, Satoru Mitsuboshi², Kaoru Suzuki¹, Masami Nishihara¹, Kazuhisa Uchiyama¹

Affiliations

¹ Department of Pharmacy, Osaka Medical College Hospital, Takatsuki, Japan.
² Department of Pharmacy, Kaetsu Hospital, Niigata, Japan.

PMID: 34117712
DOI: 10.1111/bcpt.13618

No abstract available

Keywords: creatine phosphokinase; daptomycin; muscle toxicity; rhabdomyolysis; statin.

MeSH terms

Adverse Drug Reaction Reporting Systems / statistics & numerical data
Aged
Anti-Bacterial Agents / administration & dosage
Anti-Bacterial Agents / adverse effects*
Daptomycin / administration & dosage
Daptomycin / adverse effects*
Drug Interactions
Female
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors / administration & dosage
Hydroxymethylglutaryl-CoA Reductase Inhibitors / adverse effects*
Japan
Male
Muscular Diseases / chemically induced*
Muscular Diseases / epidemiology

Substances

Anti-Bacterial Agents
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Daptomycin