Transient Horner syndrome associated with COVID-19: A case report

Mika S Naor; Paul G Mathew; Roni Sharon

doi:10.1016/j.ensci.2021.100349

Transient Horner syndrome associated with COVID-19: A case report

eNeurologicalSci. 2021 Dec:25:100349. doi: 10.1016/j.ensci.2021.100349. Epub 2021 Jun 15.

Authors

Mika S Naor^{1

2}, Paul G Mathew^{3

4

5}, Roni Sharon^{1

6}

Affiliations

¹ University of Tel Aviv, Sackler School of Medicine New York State/American Program, Tel Aviv, Israel.
² State University of New York at Geneseo, Department of Psychology, Geneseo, NY, United States of America.
³ Brigham & Women's Hospital, Department of Neurology, Boston, MA 02115, United States of America.
⁴ Harvard Vanguard Medical Associates, Department of Neurology, Braintree, MA, United States of America.
⁵ Harvard Medical School, Boston, MA, United States of America.
⁶ Sheba Medical Center, Department of Neurology, Ramat Gan, Israel.

Abstract

The Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19), has spread as a global pandemic with significant morbidity and mortality. As the prevalence of COVID-19 has risen, so has the diversity of its clinical presentation. SARS-CoV-2 is considered to have neuroinvasive and neurotropic qualities that can lead to central and peripheral nervous system manifestations. We describe a 65-year-old woman who developed new-onset unilateral ptosis and mitosis following a diagnosis of COVID-19. To our knowledge, this is the first reported case describing transient Horner syndrome in association with COVID-19.

Keywords: COVID-19; Horner syndrome; Nervous system; Neuroinvasion; Neurological symptoms; Novel coronavirus.