Cobalt plaque versus enucleation for uveal melanoma: comparison of survival rates

Br J Ophthalmol. 1988 Jul;72(7):494-7. doi: 10.1136/bjo.72.7.494.

Abstract

Two hundred and twenty-three patients treated by cobalt plaque for uveal melanoma were compared with 416 patients treated by enucleation for uveal melanoma in terms of patient survival. The median follow-up time for the patients treated by cobalt plaque was 4.3 years. Kaplan-Meier survival curves were calculated up to five years following treatment based on time to tumour-related deaths. Cox's proportional hazards multivariate analysis was performed to determine which variables were related to melanoma-related deaths while controlling for age, size, and location of the tumours. Statistically significant predictive factors were location of tumour and largest tumour dimension. There was not a statistically significant difference in survival between patients treated by cobalt plaque and those treated by enucleation.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Cobalt Radioisotopes / therapeutic use
  • Humans
  • Melanoma / mortality
  • Melanoma / radiotherapy*
  • Melanoma / surgery
  • Middle Aged
  • Time Factors
  • Uveal Neoplasms / mortality
  • Uveal Neoplasms / radiotherapy*
  • Uveal Neoplasms / surgery

Substances

  • Cobalt Radioisotopes