BCOR immunohistochemistry, but not SATB2 immunohistochemistry, is a sensitive and specific diagnostic biomarker for central nervous system tumours with BCOR internal tandem duplication

Histopathology. 2021 Nov;79(5):891-894. doi: 10.1111/his.14439. Epub 2021 Sep 20.

Authors

Laïla Mardi¹, Arnault Tauziède-Espariat^{1

2

3}, Delphine Guillemot⁴, Gaelle Pierron^{4

5}, Priscille Gigant¹, Leïla Mehdi¹, Charlotte Berthaud¹, Noémie Pucelle¹, Joelle Lacombe¹, Lauren Hasty¹, Ellen Wahler¹, Fabrice Chrétien^{1

3}, Emmanuèle Lechapt^{1

3}, Pascale Varlet^{1

2

3}

Affiliations

¹ Department of Neuropathology, GHU Paris, Psychiatry and Neurosciences, Sainte-Anne Hospital.
² Institute of Psychiatry and Neurosciences de Paris (IPNP), UMR S1266, INSERM, IMA-BRAIN.
³ Université de Paris.
⁴ Laboratory of Somatic Genetics, Curie Institute Hospital.
⁵ Paris-Sciences-Lettres, Curie Institute Research Centre, INSERMU830, Paris, France.

PMID: 34196010
DOI: 10.1111/his.14439

No abstract available

Publication types

Letter

MeSH terms

Biomarkers, Tumor*
Central Nervous System Neoplasms* / diagnosis
Central Nervous System Neoplasms* / pathology
Female
Humans
Immunohistochemistry*
Male
Matrix Attachment Region Binding Proteins
Proto-Oncogene Proteins / genetics*
Repressor Proteins / genetics*
Transcription Factors

Substances

BCOR protein, human
Biomarkers, Tumor
Matrix Attachment Region Binding Proteins
Proto-Oncogene Proteins
Repressor Proteins
SATB2 protein, human
Transcription Factors