Elevated Interleukin-10 Levels in COVID-19: Potentiation of Pro-Inflammatory Responses or Impaired Anti-Inflammatory Action?

Front Immunol. 2021 Jun 21:12:677008. doi: 10.3389/fimmu.2021.677008. eCollection 2021.

Authors

Hashim Islam¹, Thomas C Chamberlain^{2

3}, Alice L Mui^{2

3}, Jonathan P Little¹

Affiliations

¹ School of Health and Exercise Sciences, University of British Columbia Okanagan, Kelowna, BC, Canada.
² Department of Surgery, University of British Columbia, Vancouver, BC, Canada.
³ Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada.

No abstract available

Keywords: SARS – CoV – 2; cytokine storm; diabetes; immunometabolism; inflammation.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Anti-Inflammatory Agents / metabolism*
COVID-19 / immunology*
Cytokine Release Syndrome / immunology*
Humans
Inflammation / immunology
Inflammation / metabolism*
Inflammation Mediators / metabolism*
Interleukin-10 / immunology
Interleukin-10 / metabolism*
SARS-CoV-2 / physiology*
Up-Regulation

Substances

Anti-Inflammatory Agents
Inflammation Mediators
Interleukin-10