Oncoplastic breast-conservative surgery for breast cancers: a uni-institutional case-control study

Future Oncol. 2021 Oct;17(29):3843-3852. doi: 10.2217/fon-2021-0280. Epub 2021 Jul 16.

Abstract

The current study was designed to compare oncological outcomes between oncoplastic (OBCS) and conventional breast-conserving surgery (BCS). Data collected retrospectively from two groups of patients diagnosed with breast cancer, cases group (OBCS) and control group (BCS), were analyzed. A total of 277 women were included in the analysis: 193 (69.7%) in the cases group and 84 (30.3%) in the control group. Resected volume was larger in the OBCS group (438.05 ± 302.26 cm3 vs 223.34 ± 161.75 cm3; p < 0.001). Re-excision was required for 7.1% of patients receiving BCS versus 4.7% in the OBCS group (p = 0.402). After long-term follow up, no local recurrences occurred in the OBCS group, while 2.4% of patients receiving BCS had local relapse (p = 0.045). Compared with BCS, OBCS increases oncological safety in terms of re-excision rate and local recurrence.

Keywords: breast cancer; breast-conserving surgery; case-control; oncoplastic breast conserving surgery; re-excision; recurrence.

MeSH terms

  • Adult
  • Aged
  • Breast Neoplasms / surgery*
  • Case-Control Studies
  • Female
  • Humans
  • Mastectomy, Segmental*
  • Middle Aged
  • Retrospective Studies
  • Treatment Outcome