Epicardial Nodules as the Initial Manifestation of Immunoglobulin G4-Related Pericarditis

Hiroyuki Yamamoto; Keiko Ohta-Ogo; Jun Isogai; Hatsue Ishibashi-Ueda; Yoshitsugu Nakamura

doi:10.1016/j.jaccas.2020.05.092

Epicardial Nodules as the Initial Manifestation of Immunoglobulin G4-Related Pericarditis

JACC Case Rep. 2020 Aug 19;2(10):1505-1509. doi: 10.1016/j.jaccas.2020.05.092. eCollection 2020 Aug.

Authors

Hiroyuki Yamamoto¹, Keiko Ohta-Ogo², Jun Isogai³, Hatsue Ishibashi-Ueda², Yoshitsugu Nakamura⁴

Affiliations

¹ Department of Cardiovascular Medicine, Narita-Tomisato Tokushukai Hospital, Chiba, Japan.
² Department of Pathology, National Cerebral and Cardiovascular Center, Suita, Japan.
³ Department of Radiology, Asahi General Hospital, Asahi, Japan.
⁴ Department of Cardiovascular Surgery, Chiba-Nishi General Hospital, Matsudo, Japan.

Abstract

Immunoglobulin G4 (IgG4)-related pericarditis, an immune-mediated fibro-inflammatory condition, is a rare yet life-threatening disease presenting with constrictive pericarditis. We describe a case of IgG4-related pericarditis presenting with epicardial nodules successfully treated with corticosteroids. This case highlights the clinical significance of assessing IgG4-related pericarditis in the diagnostic workup of pericardial masses. (Level of Difficulty: Advanced.).

Keywords: CCTA, coronary computed tomography angiography; CMR, cardiac magnetic resonance; CP, constrictive pericarditis; FDG PET/CT, fluorodeoxyglucose positron-emission tomography/computed tomography; IgG4, immunoglobulin G4; IgG4-RD, immunoglobulin G4–related disease; PE, pericardial effusion; cardiac magnetic resonance; computed tomography; immunoglobulin G4–related disease; immunoglobulin G4–related pericarditis; pericardial effusion.

Publication types

Case Reports