Combating information chaos: a case for collaborative clinical guidelines in a pandemic

Cell Rep Med. 2021 Aug 17;2(8):100375. doi: 10.1016/j.xcrm.2021.100375. Epub 2021 Jul 27.

Abstract

The speed and scale of new information during the COVID-19 pandemic required a new approach toward developing best practices and evidence-based clinical guidance. To address this need, we produced COVIDProtocols.org, a collaborative, evidence-based, digital platform for the development and dissemination of COVID-19 clinical guidelines that has been used by over 500,000 people from 196 countries. We use a Collaborative Writing Application (CWA) to facilitate an expedited expert review process and a web platform that deploys content directly from the CWA to minimize any delays. Over 200 contributors have volunteered to create open creative-commons content that spans over 30 specialties and medical disciplines. Multiple local and national governments, hospitals, and clinics have used the site as a key resource for their own clinical guideline development. COVIDprotocols.org represents a model for efficiently launching open-access clinical guidelines during crisis situations to share expertise and combat misinformation.

Trial registration: ClinicalTrials.gov NCT04389671.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • COVID-19 / therapy*
  • COVID-19 / transmission
  • Evidence-Based Practice / methods*
  • Humans
  • Information Dissemination / methods*
  • Pandemics / prevention & control
  • Practice Guidelines as Topic* / standards
  • SARS-CoV-2 / pathogenicity

Associated data

  • ClinicalTrials.gov/NCT04389671