Localized Darier disease: three cases of Type 1 segmental mosaicism

Clin Exp Dermatol. 2022 Jan;47(1):167-169. doi: 10.1111/ced.14866. Epub 2021 Sep 1.

Abstract

Darier disease (DD) is an autosomal dominant acantholytic dermatosis with an estimated prevalence of 1 in 30 000-100 000. A localized form of DD was first described by Kreibich in 1906 and is thought to account for 10% of all cases. A number of clinical variants have been reported including: unilateral, linear, segmental or zosteriform DD. We present a case series of three patients with localized DD.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Age of Onset
  • Aged
  • Darier Disease / classification
  • Darier Disease / genetics*
  • Darier Disease / pathology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Mosaicism*