Phantom epistasis between unlinked loci
Nature
.
2021 Aug;596(7871):E1-E3.
doi: 10.1038/s41586-021-03765-z.
Epub 2021 Aug 11.
Authors
Gibran Hemani
#
1
2
,
Joseph E Powell
#
3
4
,
Huanwei Wang
5
,
Konstantin Shakhbazov
,
Harm-Jan Westra
6
,
Tonu Esko
7
8
9
,
Anjali K Henders
5
,
Allan F McRae
5
,
Nicholas G Martin
10
,
Andres Metspalu
7
,
Lude Franke
6
,
Grant W Montgomery
5
,
Michael E Goddard
11
,
Greg Gibson
12
,
Jian Yang
#
5
13
14
,
Peter M Visscher
#
5
Affiliations
1
MRC Integrative Epidemiology Unit, University of Bristol, Oakfield House, Oakfield Grove, Bristol, UK. g.hemani@bristol.ac.uk.
2
Population Health Sciences, University of Bristol, Bristol, UK. g.hemani@bristol.ac.uk.
3
UNSW Cellular Genomics Futures Institute, School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia.
4
Garvan-Weizmann Centre for Cellular Genomics, Garvan Institute of Medical Research, Sydney, New South Wales, Australia.
5
Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia.
6
Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
7
Estonian Genome Center, University of Tartu, Tartu, Estonia.
8
Medical and Population Genetics, Broad Institute, Cambridge, MA, USA.
9
Divisions of Endocrinology, Children's Hospital, Boston, MA, USA.
10
Queensland Institute of Medical Research, Brisbane, Queensland, Australia.
11
Faculty of Veterinary and Agricultural Science, University of Melbourne, Melbourne, Victoria, Australia.
12
School of Biology and Centre for Integrative Genomics, Georgia Institute of Technology, Atlanta, GA, USA.
13
School of Life Sciences, Westlake University, Hangzhou, Zhejiang, China.
14
Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, Zhejiang, China.
#
Contributed equally.
PMID:
34381229
DOI:
10.1038/s41586-021-03765-z
No abstract available
Publication types
Letter
Comment
MeSH terms
Epistasis, Genetic*
Models, Genetic*
Grants and funding
208806/Z/17/Z/WT_/Wellcome Trust/United Kingdom