Hereditary colorectal cancer syndromes and the COVID-19 pandemic: results from a survey conducted in patients enrolled in a dedicated registry

Qual Life Res. 2022 Apr;31(4):1105-1115. doi: 10.1007/s11136-021-02973-4. Epub 2021 Aug 23.

Abstract

Purpose: The coronavirus 2019 (COVID-19) pandemic has had profound consequences also for non-infected patients. This study aimed to evaluate the impact of the pandemic on the quality of life of a population with hereditary gastrointestinal cancer predisposition syndromes and on the surveillance/oncological care program of patients enrolled in a dedicated registry.

Methods: The study was conducted by means of an online self-report survey during the first Italian national lockdown. The survey comprised four sections: demographics; perception/knowledge of COVID-19; impact of the COVID-19 pandemic on surveillance and cancer care; health status (SF-12 questionnaire).

Results: 211 complete questionnaires were considered. 25.12% of respondents reported being not at all frightened by COVID-19, 63.98% felt "not at all" or "a little" more fragile than the healthy general population, and 66.82% felt the coronavirus to be no more dangerous to them than the healthy general population. 88.15% of respondents felt protected knowing they were monitored by a team of dedicated professionals.

Conclusion: Patients with hereditary gastrointestinal cancer predisposition syndromes reported experiencing less fear related to COVID-19 than the healthy general population. The study results suggest that being enrolled in a dedicated registry can reassure patients, especially during health crises.

Keywords: Coronavirus pandemic; Familial polyposis; Hereditary gastrointestinal cancer syndromes; Lynch syndrome; Registry; SF-12 questionnaire.

MeSH terms

  • COVID-19* / epidemiology
  • Colorectal Neoplasms*
  • Communicable Disease Control
  • Humans
  • Pandemics
  • Quality of Life / psychology
  • Registries
  • SARS-CoV-2
  • Surveys and Questionnaires
  • Syndrome