Transposon debris in ciliate genomes

PLoS Biol. 2021 Aug 24;19(8):e3001354. doi: 10.1371/journal.pbio.3001354. eCollection 2021 Aug.

Abstract

The germline genomes of ciliated protists are replete with "junk" DNA insertions that need to be removed for gene expression. Unlike introns, these are spliced as DNA. What is their source, and why are they so abundant? A new study in PLOS Biology supports a classic model of transposon origins.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Comment

MeSH terms

  • Ciliophora* / genetics
  • Genome* / genetics
  • Germ Cells
  • Introns / genetics