Mumps outbreak among fully vaccinated school-age children and young adults, Portugal 2019/2020

Epidemiol Infect. 2021 Aug 27:149:e205. doi: 10.1017/S0950268821002028.

Abstract

On 16-17 January 2020, four suspected mumps cases were reported to the local Public Health Authorities with an epidemiological link to a local school and football club. Of 18 suspected cases identified, 14 were included in this study. Laboratory results confirmed mumps virus as the cause and further sequencing identified genotype G. Our findings highlight that even with a high MMR vaccine coverage, mumps outbreaks in children and young adults can occur. Since most of the cases had documented immunity for mumps, we hypothesise that waning immunity or discordant mumps virus strains are likely explanations for this outbreak.

Keywords: MMR vaccination; Mumps; Outbreaks; Vaccine preventable diseases; Virology.

MeSH terms

  • Adolescent
  • Child
  • Disease Outbreaks* / prevention & control
  • Female
  • Genotype
  • Humans
  • Male
  • Measles-Mumps-Rubella Vaccine / administration & dosage*
  • Measles-Mumps-Rubella Vaccine / genetics
  • Measles-Mumps-Rubella Vaccine / immunology
  • Mumps / epidemiology*
  • Mumps / prevention & control
  • Mumps / virology
  • Mumps virus / genetics
  • Mumps virus / immunology*
  • Mumps virus / pathogenicity
  • Portugal / epidemiology
  • Vaccination / statistics & numerical data
  • Young Adult

Substances

  • Measles-Mumps-Rubella Vaccine