Objective: To observe the therapeutic effect of horizontal penetration needling combined with rizatriptan monobenzoate tablets, simple horizontal penetration needling and simple rizatriptan monobenzoate tablets for migraine without aura in acute stage.
Methods: A total of 99 patients with migraine without aura in acute stage were randomized into an acupuncture plus medication group, an acupuncture group and a western medication group, 33 cases in each one. In the acupuncture group, horizontal penetration needling was applied once at Hanyan (GB 4) to Xuanli(GB 6), Shenting (GV 24) to Yintang (GV 29), Baihui (GV 20) to Qianding (GV 21), etc. for 2 h. In the western medication group, oral rizatriptan monobenzoate tablets for 10 mg were given once. In the acupuncture plus medication group, treatment of acupuncture combined with rizatriptan monobenzoate tablets were given, the application was the same as the acupuncture group and the western medication group. Before treatment and 0.5, 2, 24 h after treatment, the visual analogue scale (VAS) score was observed, the remission rate and the disappearance rate of migraine of 2, 24 h after treatment were compared in the 3 groups.
Results: Compared before treatment, the VAS scores of each time point after treatment were decreased in the 3 groups (P<0.05), and the changes in the acupuncture plus medication group were greater than those in the acupuncture group and the western medication group (P<0.05). The remission rates of 24 h after treatment and the disappearance rates of migraine of 2, 24 h after treatment in the acupuncture plus medication group were higher than those in the acupuncture group and the western medication group (P<0.05).
Conclusion: Horizontal penetration needling combined with rizatriptan monobenzoate tablets have significant therapeutic effect on rapid analgesia and continuous analgesia for migraine without aura in acute stage, its effect is superior to simple horizontal penetration needling and simple rizatriptan monobenzoate tablets.
目的：观察排针平刺法联合苯甲酸利扎曲普坦片与单纯排针平刺法、苯甲酸利扎曲普坦片治疗无先兆偏头痛急性期的疗效。方法：将99例无先兆偏头痛急性期患者随机分为针药组、针刺组和西药组，每组33例。针刺组予排针平刺法治疗，穴取颔厌-悬厘、神庭-印堂、百会-前顶等，留针2 h，针刺1次；西药组予口服10 mg苯甲酸利扎曲普坦片1次；针药组采用排针平刺法（同针刺组）联合口服苯甲酸利扎曲普坦片（同西药组）治疗。于治疗前，治疗后0.5、2、24 h观察各组患者疼痛视觉模拟量表（VAS）评分，比较各组治疗后2、24 h头痛缓解率、消失率。结果：各组治疗后不同时点VAS评分较治疗前降低（P<0.05），且针药组降低幅度大于针刺组、西药组（P<0.05）。针药组治疗后2、24 h头痛消失率及治疗后24 h头痛缓解率高于针刺组、西药组（P<0.05）。结论：排针平刺法联合苯甲酸利扎曲普坦片治疗无先兆偏头痛急性期在快速镇痛、持续镇痛方面疗效显著，优于单纯排针平刺法和口服苯甲酸利扎曲普坦片。.
Keywords: horizontal penetration needling; migraine without aura, acute stage; randomized controlled trial (RCT); rizatriptan monobenzoate tablets; visual analogue scale (VAS) score.