COVID-19 vaccines: Keeping pace with SARS-CoV-2 variants

Cell. 2021 Sep 30;184(20):5077-5081. doi: 10.1016/j.cell.2021.09.010. Epub 2021 Sep 17.

Abstract

As the SARS-CoV-2 pandemic evolves, new variants continue to emerge. Some highly transmissible variants, such as Delta, also raised concerns about the effectiveness provided by current vaccines. Understanding immunological correlates of protection and how laboratory findings correspond to clinical effectiveness is imperative to shape future vaccination strategies.

MeSH terms

  • Antibodies, Neutralizing / immunology
  • Antibodies, Viral / immunology
  • COVID-19 / epidemiology*
  • COVID-19 / immunology
  • COVID-19 / prevention & control*
  • COVID-19 / virology
  • COVID-19 Vaccines / classification
  • COVID-19 Vaccines / immunology*
  • Humans
  • Immunity, Cellular
  • Immunogenicity, Vaccine
  • Mutation
  • Pandemics / prevention & control*
  • SARS-CoV-2 / genetics
  • SARS-CoV-2 / immunology*
  • Vaccination / methods*

Substances

  • Antibodies, Neutralizing
  • Antibodies, Viral
  • COVID-19 Vaccines