In fall 2020, a coronavirus disease cluster comprising 16 cases occurred in Connecticut, USA. Epidemiologic and genomic evidence supported transmission among persons at a school and fitness center but not a workplace. The multiple transmission chains identified within this cluster highlight the necessity of a combined investigatory approach.
Keywords: 2019 novel coronavirus disease; COVID-19; Connecticut; SARS-CoV-2; United States; cluster; community transmission; coronavirus disease; coronaviruses; fitness center; genomic epidemiology; respiratory infections; school; severe acute respiratory syndrome coronavirus 2; transmission; viruses; zoonoses.