Clinical Influenza Testing Practices in Hospitalized Children at United States Medical Centers, 2015-2018

Mark W Tenforde; Angela P Campbell; Marian G Michaels; Christopher J Harrison; Eileen J Klein; Janet A Englund; Rangaraj Selvarangan; Natasha B Halasa; Laura S Stewart; Geoffrey A Weinberg; John V Williams; Peter G Szilagyi; Mary A Staat; Julie A Boom; Leila C Sahni; Monica N Singer; Parvin H Azimi; Richard K Zimmerman; Monica M McNeal; H Keipp Talbot; Arnold S Monto; Emily T Martin; Manjusha Gaglani; Fernanda P Silveira; Donald B Middleton; Jill M Ferdinands; Melissa A Rolfes

doi:10.1093/jpids/piab096

Clinical Influenza Testing Practices in Hospitalized Children at United States Medical Centers, 2015-2018

J Pediatric Infect Dis Soc. 2022 Jan 27;11(1):5-8. doi: 10.1093/jpids/piab096.

Authors

Mark W Tenforde¹, Angela P Campbell¹, Marian G Michaels², Christopher J Harrison³, Eileen J Klein⁴, Janet A Englund⁴, Rangaraj Selvarangan³, Natasha B Halasa⁵, Laura S Stewart⁵, Geoffrey A Weinberg⁶, John V Williams², Peter G Szilagyi⁷, Mary A Staat⁸, Julie A Boom^{9

10}, Leila C Sahni^{9

10}, Monica N Singer¹¹, Parvin H Azimi¹¹, Richard K Zimmerman¹², Monica M McNeal¹³, H Keipp Talbot⁵, Arnold S Monto¹⁴, Emily T Martin¹⁴, Manjusha Gaglani¹⁵, Fernanda P Silveira¹², Donald B Middleton¹², Jill M Ferdinands¹, Melissa A Rolfes¹

Affiliations

¹ Influenza Division, National Center for Immunization and Respiratory Disease, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
² UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
³ University of Missouri-Kansas City School of Medicine, Children's Mercy-Kansas City, Kansas City, Missouri, USA.
⁴ Department of Pediatrics, Seattle Children's Hospital, Seattle, Washington, USA.
⁵ Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
⁶ Department of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA.
⁷ Department of Pediatrics, UCLA Mattel Children's Hospital, Los Angeles, California, USA.
⁸ Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
⁹ Texas Children's Hospital, Houston, Texas, USA.
¹⁰ Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.
¹¹ Department of Infectious Diseases, UCSF Benioff Children's Hospital Oakland, Oakland, California, USA.
¹² Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
¹³ Department of Pediatrics, University of Cincinnati College of Medicine, Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
¹⁴ Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.
¹⁵ Baylor Scott and White Health, Texas A&M University College of Medicine, Temple, Texas, USA.

Abstract

At nine US hospitals that enrolled children hospitalized with acute respiratory illness (ARI) during 2015-2016 through 2017-2018 influenza seasons, 50% of children with ARI received clinician-initiated testing for influenza and 35% of cases went undiagnosed due to lack of clinician-initiated testing. Marked heterogeneity in testing practice was observed across sites.

Keywords: RT-PCR; antigen test; hospitalized; influenza; testing.

© The Author(s) 2021. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

MeSH terms

Child
Child, Hospitalized
Hospitals
Humans
Infant
Influenza, Human* / diagnosis
Respiratory Tract Infections*
Seasons
United States

Abstract

MeSH terms

Grants and funding