Factors influencing perinatal outcomes in women with preterm preeclampsia: A secondary analysis of the PHOENIX trial

Pregnancy Hypertens. 2021 Dec:26:91-93. doi: 10.1016/j.preghy.2021.10.002. Epub 2021 Oct 13.

Abstract

This secondary analysis of the PHOENIX trial (evaluating planned delivery against expectant management in late preterm preeclampsia) demonstrates that in women who started induction of labour, 63% of women delivered vaginally (56% at 34 weeks' gestation). Compared to expectant management, planned delivery was associated with higher rates of neonatal unit admission for prematurity (but lower proportions of small-for-gestational age infants); length of neonatal unit stay and neonatal morbidity (including respiratory support) were similar across both intervention groups at all gestational windows. Neonatal unit admission was increased by earlier gestation at delivery, development of severe preeclampsia, and being small-for-gestational age.

Keywords: Delivery; Perinatal; Preeclampsia; Pregnancy; Preterm.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial

MeSH terms

  • Delivery, Obstetric / statistics & numerical data*
  • Female
  • Follow-Up Studies
  • Humans
  • Infant, Premature
  • Intensive Care Units, Neonatal / statistics & numerical data
  • Labor, Induced / statistics & numerical data
  • Pre-Eclampsia / physiopathology*
  • Pregnancy
  • Pregnancy Outcome / epidemiology
  • Watchful Waiting / statistics & numerical data