18F-FDG PET/CT and 68Ga-FAPI-04 PET/CT Findings of Abdominal Leiomyosarcoma

Clin Nucl Med. 2021 Dec 1;46(12):e594-e597. doi: 10.1097/RLU.0000000000003673.

Abstract

A 56-year-old woman presented with abdominal pain and vomiting. Her abdominal CT revealed an retroperitoneal mass in the left upper quadrant of the abdomen. 18F-FDG PET/CT performed for metabolic characterization showed low to moderate heterogenous FDG uptake. 68Ga-fibroblast activation protein-specific inhibitor (FAPI)-04 PET/CT performed according to a research carried out in our department showed high heterogenous radiopharmaceutical uptake. The patient was diagnosed with leiomyosarcoma after R0 tumor resection. This case showed that 68Ga-FAPI-04 PET/CT could be a promising radiopharmaceutical in the evaluation of leiomyosarcomas.

Publication types

  • Case Reports

MeSH terms

  • Abdomen
  • Female
  • Fluorodeoxyglucose F18
  • Humans
  • Leiomyosarcoma* / diagnostic imaging
  • Middle Aged
  • Positron Emission Tomography Computed Tomography*
  • Quinolines

Substances

  • 68Ga-FAPI
  • Quinolines
  • Fluorodeoxyglucose F18