MARylation meets ubiquitination in the ART of plant immunity

Catherine Gough; Ari Sadanandom

doi:10.1016/j.molcel.2021.10.006

MARylation meets ubiquitination in the ART of plant immunity

Mol Cell. 2021 Nov 18;81(22):4572-4574. doi: 10.1016/j.molcel.2021.10.006.

Authors

Catherine Gough¹, Ari Sadanandom²

Affiliations

¹ Department of BioSciences, University of Durham, South Road, Durham DH1 3LE, UK.
² Department of BioSciences, University of Durham, South Road, Durham DH1 3LE, UK. Electronic address: ari.sadanandom@durham.ac.uk.

PMID: 34798042
DOI: 10.1016/j.molcel.2021.10.006

Abstract

In this issue of Molecular Cell, Kong et al. (2021) report that in Arabidopsis, immune elicitation promotes mono(ADP-ribosyl)ation (MARylation) of immune regulators SZP1 and SZP2 by a noncanonical ADP-ribosyltransferase, SRO2. MARylation results in stabilization of SZF1 by antagonizing its ubiquitin mediated proteasomal degradation. Consequently, these MARylation events ensure appropriate immune responses.

Publication types

Comment

MeSH terms

ADP Ribose Transferases / genetics
ADP-Ribosylation*
Arabidopsis* / genetics
Arabidopsis* / metabolism
Plant Immunity / genetics
Ubiquitination

Substances

ADP Ribose Transferases