Abstract
Epidermal nucleolar IgG deposition in clinically normal skin reflects high serum concentrations of antibody to nucleolar antigen. This immunopathologic finding occurred in six patients with scleroderma and in two patients with a scleroderma-systemic lupus erythermatosus overlap syndrome.
Publication types
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Case Reports
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adult
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Antibodies, Antinuclear / analysis
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Cell Nucleolus / immunology
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Female
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Fluorescent Antibody Technique
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Humans
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Immunoglobulin G*
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Lupus Erythematosus, Systemic / immunology*
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Middle Aged
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Scleroderma, Systemic / immunology*
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Skin / immunology*
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Skin / ultrastructure
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Syndrome
Substances
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Antibodies, Antinuclear
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Immunoglobulin G