Anaphylaxis: Data Gaps and Research Needs

Immunol Allergy Clin North Am. 2022 Feb;42(1):187-200. doi: 10.1016/j.iac.2021.10.002.

Abstract

There are significant anaphylaxis data and knowledge gaps that result in suboptimal patient care and outcomes. To address these gaps there is need for collaborative, multidisciplinary research networks to strategically design practice changing research specific to the following anaphylaxis themes: Population Science, Basic and Translational Sciences, Acute Management, and Long-Term Management. Top priorities are to refine anaphylaxis diagnostic criteria, identify accurate diagnostic and predictive anaphylaxis biomarkers, standardize postanaphylaxis care (observation periods, hospitalization criteria), and determine immunotherapy best practices. Addressing these gaps will result in improved, optimal care and clinical outcomes for patients with or at risk of anaphylaxis.

Keywords: Anaphylaxis; Basic science; Biomarkers; Emergency department; Long-term management; Population science; Research; Translational science.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Anaphylaxis* / diagnosis
  • Anaphylaxis* / epidemiology
  • Anaphylaxis* / therapy
  • Epinephrine
  • Hospitalization
  • Humans
  • Translational Science, Biomedical

Substances

  • Epinephrine