Fever, abdominal pain, serositis, arthralgia, hearing loss, proteinuria, and a family history: Muckle Wells syndrome

Lancet. 2021 Dec 4;398(10316):2101. doi: 10.1016/S0140-6736(21)02139-5.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • Abdominal Pain / etiology*
  • Antibodies, Monoclonal, Humanized / therapeutic use
  • Arthralgia / etiology*
  • Cryopyrin-Associated Periodic Syndromes / diagnosis*
  • Cryopyrin-Associated Periodic Syndromes / drug therapy
  • Cryopyrin-Associated Periodic Syndromes / genetics*
  • Fever / etiology*
  • Hearing Loss / etiology*
  • Humans
  • Lymphadenopathy
  • Male
  • Middle Aged
  • NLR Family, Pyrin Domain-Containing 3 Protein / genetics
  • Proteinuria
  • Serositis / etiology*
  • Tomography, X-Ray Computed

Substances

  • Antibodies, Monoclonal, Humanized
  • NLR Family, Pyrin Domain-Containing 3 Protein
  • NLRP3 protein, human
  • canakinumab