The first case report of pediatric acute appendicitis caused by "Candidatus Actinobaculum timonae"

Asef Iqbal; Takumi Fujimura; Masayoshi Shinjoh; Munehiro Furuichi; Takashi Iimori; Tomoshige Umeyama; Tsuyoshi Ishida; Shojiro Morinaga; Isamu Kamimaki; Kiyofumi Ohkusu; Takao Takahashi

doi:10.1016/j.jiac.2021.11.023

The first case report of pediatric acute appendicitis caused by "Candidatus Actinobaculum timonae"

J Infect Chemother. 2022 Mar;28(3):451-454. doi: 10.1016/j.jiac.2021.11.023. Epub 2021 Dec 7.

Authors

Affiliations

¹ Department of Pediatrics, National Hospital Organization Saitama Hospital, 2-1 Suwa, Wako city Saitama, Japan.
² Department of Pediatric Surgery, National Hospital Organization Saitama Hospital, 2-1 Suwa, Wako city Saitama, Japan.
³ Department of Pediatrics, Keio University School of Medicine, 35 Shinanomachi Shinjuku-ku, Tokyo, Japan. Electronic address: m-shinjo@z2.keio.jp.
⁴ Department of Pediatrics, Keio University School of Medicine, 35 Shinanomachi Shinjuku-ku, Tokyo, Japan.
⁵ Department of Pediatric Surgery, Keio University School of Medicine, 35 Shinanomachi Shinjuku-ku, Tokyo, Japan.
⁶ Department of Diagnostic Pathology, National Hospital Organization Saitama Hospital, 2-1 Suwa, Wako city Saitama, Japan.
⁷ Department of Microbiology, Tokyo Medical University, 6-1-1 Shinjuku Shinjuku-ku, Tokyo, Japan.

PMID: 34887179
DOI: 10.1016/j.jiac.2021.11.023

Abstract

A 14-year-old boy presented to the hospital with pain in the right lower abdomen. His condition was diagnosed as acute appendicitis. An emergency operation was performed, and histopathological examination revealed an actinomycete-related organism in the excised appendicitis specimen. On 16S rRNA gene sequence analysis, "Candidatus Actinobaculum timonae" was identified, which is the first known case in a pediatric patient.

Keywords: 16S rRNA; Abdominal actinomycosis; Appendicitis; Candidatus actinobaculum timonae.

Publication types

Case Reports

MeSH terms

Acute Disease
Adolescent
Appendicitis* / surgery
Child
Humans
Male
Pain
RNA, Ribosomal, 16S / genetics

Substances

RNA, Ribosomal, 16S