Case Report: Nasal Cavity Epithelial-Myoepithelial Carcinoma With High Fluoro-D-Glucose Uptake on Positron Emission Tomography/Computed Tomography

Jacques Dzuko Kamga; Jean-Christophe Leclere; Arnaud Uguen; Karim Amrane; Ronan Abgral

doi:10.3389/fmed.2021.664520

Case Report: Nasal Cavity Epithelial-Myoepithelial Carcinoma With High Fluoro-D-Glucose Uptake on Positron Emission Tomography/Computed Tomography

Front Med (Lausanne). 2021 Dec 21:8:664520. doi: 10.3389/fmed.2021.664520. eCollection 2021.

Authors

Jacques Dzuko Kamga¹, Jean-Christophe Leclere², Arnaud Uguen³, Karim Amrane¹, Ronan Abgral^{1

4}

Affiliations

¹ Department of Nuclear Medicine, University Hospital of Brest, Brest, France.
² Department of Otorhinolaryngology, University Hospital of Brest, Brest, France.
³ Department of Pathology, University Hospital of Brest, Brest, France.
⁴ EA 3878 GETBO, IFR 148, Bretagne Loire University, Brest, France.

Abstract

Epithelial-myoepithelial carcinoma (EMC) is a rare malignant neoplasm arising most frequently in the salivary glands and exceptionally in the nasal cavity. EMC accounts for ~1-2% of salivary gland tumors. Even if the nodal and distant metastasis rates are low, tumor staging remains indicated. Here, the authors present the 2-deoxy-2-[¹⁸F]fluoro-D-glucose PET-CT (¹⁸F-FDG-PET/CT) study of a very rare case of biopsy-proven EMC of the left nasal cavity. This ¹⁸F-FDG-PET/CT was performed to stage this tumor and guide the therapeutic strategy due to an atypical high-grade presentation in immunohistochemistry. To our knowledge, this is the first case reporting such high ¹⁸F-FDG avidity of EMC of the nasal cavity in PET/CT.

Keywords: 18FDG-PET/CT; epithelial-myoepithelial carcinoma (EMC); high avidity; high grade; nasal cavity.

Publication types

Case Reports