Myeloid Sarcoma - a diagnostic challenge in paediatric practice

J Pak Med Assoc. 2021 Dec;71(12):2806-2808. doi: 10.47391/JPMA.460.

Abstract

Myeloid Sarcomas are rare tumours of myeloid origin that may infiltrate multiple sites of the body. They may precede acute myeloid leukaemia or present without it. It has non-specific manifestations and presents as a diagnostic and therapeutic challenge owing to the limited literature that reports consensus on diagnostic and treatment strategies. Immunohistochemistry is of significance in identifying the disease and acute myeloid leukaemia protocols of systemic therapy remain the mainstay of the treatment. Our report of an 11-year-old child with myeloid sarcoma aims to add to the limited existing literature and describe the varied presentation and sites of involvement.

Keywords: Myeloid Sarcoma; Acute myeloid leukaemia; Haematological malignancy; Paediatric Oncology..

Publication types

  • Case Reports

MeSH terms

  • Child
  • Humans
  • Immunohistochemistry
  • Leukemia, Myeloid, Acute* / diagnosis
  • Leukemia, Myeloid, Acute* / therapy
  • Sarcoma, Myeloid* / diagnosis