Graphene-Based Nanomaterials as Drug Delivery Carriers

Woo Yeup Jeong; Hye Eun Choi; Ki Su Kim

doi:10.1007/978-981-16-4923-3_6

Graphene-Based Nanomaterials as Drug Delivery Carriers

Adv Exp Med Biol. 2022:1351:109-124. doi: 10.1007/978-981-16-4923-3_6.

Authors

Woo Yeup Jeong¹, Hye Eun Choi¹, Ki Su Kim^{2

3}

Affiliations

¹ School of Chemical Engineering, College of Engineering, Pusan National University, Busan, South Korea.
² School of Chemical Engineering, College of Engineering, Pusan National University, Busan, South Korea. kisukim@pusan.ac.kr.
³ Institute of Advanced Organic Materials, Pusan National University, Busan, South Korea. kisukim@pusan.ac.kr.

PMID: 35175614
DOI: 10.1007/978-981-16-4923-3_6

Abstract

Graphene and graphene-based materials have been attracted in the past few years for biomedical applications due to their physicochemical and biological properties such as large surface area, chemical and mechanical stability, excellent conductivity, and good biocompatibility. Graphene-based materials not only surface modified graphene-based materials like graphene oxide (GO) or reduced graphene oxide (rGO) but also other structural forms like fullerene, carbon nanotubes, and graphite have been applied to advanced drug delivery systems. In this chapter, we review on the application of graphene-based materials in the drug delivery system with their physicochemical properties, methods for the preparation of graphene-based carriers, followed by analysis about their biodistribution and biosafety whether they are suitable as drug delivery carriers.

Keywords: Drug delivery system; Graphene; Graphene-based materials.

Publication types

Review

MeSH terms

Drug Carriers / chemistry
Drug Delivery Systems
Graphite* / chemistry
Nanostructures* / chemistry
Nanotubes, Carbon*
Tissue Distribution

Substances

Drug Carriers
Nanotubes, Carbon
Graphite