Diverticulosis Is Associated With Internal Hemorrhoids on Colonoscopy: Possible Clues to Etiology

Jared A Sninsky; Joseph Galanko; Robert S Sandler; Anne F Peery

doi:10.1016/j.cgh.2022.02.020

Diverticulosis Is Associated With Internal Hemorrhoids on Colonoscopy: Possible Clues to Etiology

Clin Gastroenterol Hepatol. 2023 Apr;21(4):1097-1099.e3. doi: 10.1016/j.cgh.2022.02.020. Epub 2022 Feb 14.

Authors

Jared A Sninsky¹, Joseph Galanko², Robert S Sandler², Anne F Peery²

Affiliations

¹ Department of Medicine, Division of Gastroenterology and Hepatology, University of North Carolina School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina. Electronic address: jared.sninsky@unchealth.unc.edu.
² Department of Medicine, Division of Gastroenterology and Hepatology, University of North Carolina School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

Abstract

Hemorrhoids are a common but poorly understood gastrointestinal condition.¹ Bowel habits and fiber consumption are frequently cited as risk factors for hemorrhoids, but research has been inconclusive.² Recent genome-wide association studies (GWAS) have suggested an association between diverticular disease and hemorrhoids.³ We sought to investigate the association between colonic diverticulosis and internal hemorrhoids to validate the prediction from the GWAS.

Publication types

Research Support, N.I.H., Extramural

MeSH terms

Colonoscopy
Diverticulosis, Colonic* / diagnosis
Diverticulum* / diagnosis
Genome-Wide Association Study
Hemorrhoids* / diagnosis
Hemorrhoids* / etiology
Humans
Risk Factors

Abstract

Publication types

MeSH terms

Grants and funding